I know what you mean, have the same problem. I take a zantac ( approved by my doctor), I take it in the
morning ( I take my blood pressure meds at 6;00PM ) I take a pink 150 zantac and it heals any stomach
upset all day and night, good luck. Lacey

Forgot to tell you, also drink lots of water.

@lugal Hello and welcome to Mayo Connect! I see that you just joined our online patient support community a few days ago. I have taken blood pressure meds for a number of years to treat an aortic valve problem. The ACE inhibitors, I take vasotech, have never caused any nausea or upset stomach, however, Beta Blockers have been difficult. I have found that taking it with a meal and drinking lots of liquid does help. Atenolol, a beta blocker, has worked the best for me with the least side effects. Have you talked with your doctor about this? Physicians have usually heard of all of the side effects and can be helpful in coming up with some suggestions. Best wishes!

Welcome to connect, @lugal,

I can empathize with you because I too, had to try several different hypertension medications before settling on one that I have taken for almost 10 years now, and am very happy with it.

I moved your message to the Heart & Blood group, under the discussion "blood pressure & hypertension" so you can meet fellow members who have talked much about blood pressure and medications. I'd like to introduce you to @dawn_giacabazi, @predictable, @patreats5674, @jacko, and @teatime.
I would also encourage you to read this Mayo Clinic article about choosing the right blood pressure medication:
http://mayocl.in/2emxkRJ

@lugal, does your doctor have any suggestions as to how you can avoid getting sick while taking these medications? What methods have you tried in the past?

Hi, @lugal. Could you tell us what meds have been prescribed for you and caused you stomach distress? That would help us zero-in on some of the dozens of medications given to hypertensives like me. I'm not the champion user of many medications, but I have sampled at least one of all of the major groups that are popular. That's due to changing doctors from time to time as well as changing medical programs from time to time. My current HMO relieved my Internal Medicine doctor of my problem and sent me over to Nephrology, where I have had my best care -- mainly because my problem is kidney-related, as most hypertension problems are. My nephrologist brought in an endocrinologist to do some hormone tests. After I developed atrial fibrillation, I added a Cardiologist to my medical team. My team leader, though, is the nephrologist.

I don't recall digestive problems from hypertension meds of any kind. This may be due to initial low dosages when a new medication is added, rising as I got accustomed to them. Most notably, though, the detailed patient label that comes with a new medication is crucial, because it clearly directs how to take the medication -- often with food, which avoids stomach upset, and sometimes with a full glass of water. When to take it is important also, and that usually comes from the prescribing doctor, which requires a good measure of friendly and regular communication.

A further complication can be conflict with other medications or supplements you are taking. Once again, your doctor is your best advisor on this, although a half-dozen web sites are available to help, and your pharmacist also can give good advice. Finally, check into that Mayo web page that @kanaazpererira suggested -- http://mayocl.in/2emxkRJ -- it provides a framework for thinking about the meds you need.