Discomfort is not the word. Tapering from 7.5 to 5 mgs Prednisone caused me to have severely aching and pain all over. Everything started to hurt. I was in excruciating pain for 4 days and finally took two Advil (which I was told after the fact that I should only take Tylenol). The pain went away. I was waiting for it come back, but it never did. They have been very slowly weaning me down on the Prednisone. I was on 3 mgs for 2 months. This morning I was told I can take 2 mg today and 3 mg tomorrow and alternate days over the next month. Not feeling too bad right now but it is early.