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Thanks @loriesco so glad it helped and so kind of you to share.
I had a bad flare two nights ago and took flurbiprofen the next morning. I use it very sparingly due to kidneys.
I just looked it up and Celebrex is a selective Cox2 and flurbiprofen is non-selective. https://www.medicalnewstoday.com/articles/list-of-nsaids-from-strongest-to-weakest#List-of-NSAIDs I am going to ask if Celebrex would be better for me (and my kidneys!): I love flurbiprofen and consider it a treat to take. I can't take it often but when I do, I have a better day. Glad Celebrex is going that for you. The quote from the link is below:
"There are two types of cyclooxygenase isoenzymes: COX-1 and COX-2. They each play slightly different roles in the body:
COX-1 helps the body maintain platelet aggregation, gastrointestinal mucosa lining, and kidney function.
COX-2 helps the body with the inflammatory response due to injury or illness.
The majority of NSAIDs are non-selective. This means they target both COX-1 and COX-2 isoenzymes. This may lead to different adverse reactions as they can affect different systems in the body.
Selective, also known as COX-2 selective, only targets COX-2. Currently, in the United States, celecoxib is the only NSAID available in this group.
By selectively targeting only COX-2, celecoxib can help with inflammation without affecting other systems in the body, such as the kidneys."
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Yes, Celebrex and its generic are COX 2 inhibitors. They are the ONLY drugs in the class of NSAID that actually INHIBITS production of inflammation-causing enzymes (COX 2) in your body, https://www.goodrx.com/classes/nsaids/is-celebrex-better-than-ibuprofen
It also has less gastric issues. Less hard on kidneys. It also is the ONLY drug you can continue taking before surgery (besides Tylenol) because it doesn't thin or thicken your blood.
It is more than a mask. After doing this all for 35 years I am very very careful (as you seem to be) as to what medications I use. The other NSAIDS will do a lot to relieve pain but they are very hard on your body if injested. I will use aspirin, diclofenac, capsicum, lidocaine, and hydrocortisone as TOPICAL ONLY pain controllers. Vioxx poisoned me and Ibuprofen put me in the hospital. I will take Toradol (Ketorolac) for a crisis of sacral or sciatic pain once in a blue moon. I took it for the flare of the trigeminal neuralgia 2 weeks ago a couple times. But its really bad for you, too. The Celebrex is much better. It is an advanced therapeutic when compared to the older Cox 2/Cox 1 meds. Of course -- insurance always holds back the BEST medicine wanting people to take all the cheap garbage they want to contract for. Lucky I am lactose/gluten intolerant I can get the better ones. However -- celebrex is the ONLY drug I can't find without lactose. So I take a lactaid pill when I take it. I would never take fu
I read last night that L Carnitine is actually a nerve pain reliever. Who know? (It doesn't relieve my pain!) but it's doing a great job of bringing my energy and metabolism back. I forgot to address the low cortisol. I read up and I see why you connect the low cortisol to .... oh geez, I forgot... was it the L Carnitine?) I wasn't using it at the time and I might have cortisol burnout or some prediabetes going on. I'm pretty sure it will snap back when I get tested again. think that midriff bulge and the low cortisol also went together.
I wouldn't take the flurbiprofen because it is in the same class of NSAIDs as the ibuprofen, piroxicam, etc. High blood pressure, edema, anxiety causing, etc. just ibuprofen for a couple days if I pull a muscle in my lower back once a year. I really like the low-dose Percocet 10/325 best after 25 years. No gastric issues and it doesn't conflict with anything and my labs are stable. No addiction since I started it just to stop back pain that doctors can't resolve. That's all it does is handle that pain. If I ever get a "sudden" thing like gout pain or the new TN it will help that too. If the moon and stars align -- and I have no pain -- I don't take it, even after 25 years of daily use.