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Osteoporosis & Bone Health | Last Active: Aug 20 8:30pm | Replies (14)
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Replies to "Excited to tell you @windyshores i had a trigeminal neuralgia flare last night and took Celebrex..."
Thanks @loriesco so glad it helped and so kind of you to share.
I had a bad flare two nights ago and took flurbiprofen the next morning. I use it very sparingly due to kidneys.
I just looked it up and Celebrex is a selective Cox2 and flurbiprofen is non-selective. https://www.medicalnewstoday.com/articles/list-of-nsaids-from-strongest-to-weakest#List-of-NSAIDs I am going to ask if Celebrex would be better for me (and my kidneys!): I love flurbiprofen and consider it a treat to take. I can't take it often but when I do, I have a better day. Glad Celebrex is going that for you. The quote from the link is below:
"There are two types of cyclooxygenase isoenzymes: COX-1 and COX-2. They each play slightly different roles in the body:
COX-1 helps the body maintain platelet aggregation, gastrointestinal mucosa lining, and kidney function.
COX-2 helps the body with the inflammatory response due to injury or illness.
The majority of NSAIDs are non-selective. This means they target both COX-1 and COX-2 isoenzymes. This may lead to different adverse reactions as they can affect different systems in the body.
Selective, also known as COX-2 selective, only targets COX-2. Currently, in the United States, celecoxib is the only NSAID available in this group.
By selectively targeting only COX-2, celecoxib can help with inflammation without affecting other systems in the body, such as the kidneys."