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Choosing Our Poison
Our bodies are very complex entities. The drugs used to treat Osteoporosis can also affect other functions but that often seems to be ignored or glossed over. I wish some expert would be brave enough to publish a paper listing the possible ramifications for each drug.
For Tymlos and Forteo, the medication also controls abdominal fat formation.
For Evenity, Sclerstin moderation may also play a role in plaque in coronary arteries.
Prolia decreases immunity.
Those are a few examples that come quickly to my mind ad I admit I may be in error on these
We NEED to be aware of what other functions could be affected to choose wisely. I have a bone cancer with my immunity already being depressed. I need a drug that does not depress that further or have a negative effect on my bone marrow.
Doctors and pharmaceutical companies must start treating us a whole entities and not just bones.
Enough with my rant.
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Not enough, do continue.
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1 ReactionDoesn't sound like a rant..,...just good info for all of us to use.
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3 ReactionsI couldn't agree more! So many questions we're left with.
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1 ReactionMaybe instead of using the term "side effects" to describe what I am referring to, a better term might be "co-effects.". That would give them more importance.
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4 Reactions@normahorn You wrote that you wished an expert had published an article in the ramifications for each of the osteoporosis medications. I’m wondering if you might like to do a literature search. If not, you could try Google Scholar where you are more likely to find peer-reviewed scientific articles.
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3 ReactionsI would like to see one peer reviewed article addressing this issue rather than each of us having to search though many, many articles. I would like to see it addressed in an upfront manner. Imagine our providers having access to something more than just what the effect on bones is. And relegating anything inconvenient to a side effect.
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8 ReactionsIn my experience doctors are not aware of many side effects that are actually listed on the drug sites. It is hard hearing "I haven't run into this with anyone else" or even "that's strange" when the side effect is viewable within seconds. I am not sure why this is.
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10 ReactionsThey're probably under pressure from the pharmaceutical companies to push the drugs!
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2 ReactionsWhen I asked my doctor about side effects of Evenity he said he couldn't really answer what would happen if I took the drug. Some people have no side effects, some have side effects that are manageable, and some have interolerable ones. There was no way to know.
He added that the side effect of doing nothing WAS knowable ... debilitating fractures and long lasting pain.
Well, when he put it that way, it seems worth a try. He did say to call his office if I run into unpleasant side effects.
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3 ReactionsAgain, I am not talking about side effects but reactions that are fundamental to the way a drug works. Some people can afford a decrease in immunity; those who are immunocompromised cannot. If sclerstin suppression would also suppress healthy bone marrow activity, I am not willing to have my cancer go from stage 0 to even stage 1.
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