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@spaceguy
Since you have not had radiation treatments you cannot discuss this is your R/O who could go over the points of rising PSA numbers. Slight fluctuation are completely normal but yours going up that much is not slight. Prior to that test did you refrain from bike riding? How about other activities that can make PSA rise in prostrate.
All those items are good topics for discussion with your urologist. Just pick a reliable one with extensive experience in prostrate cancer and treatments. I had a PSA level of 3.75. That is below normal level of 4.0. However my PCP did not like my PSA rising each time I had a PSA test. It never went back down just steadily climbing. Thus referral to urologist who did MRI found suspicious area, then biopsies and prostrate cancer diagnosis. So it is the steady rising of PSA numbers not really the actual number that is important to monitor as it indicates issues with prostrate most likely but no always prostrate cancer.
A DME can detect a noctual but cannot micorscopic detect prostrate cancer. My DME were all normal. I just had one yesterday at UFHPTI a year after my proton radiation treatments ended. My PSA at the 1 year mark was 0.44 and had steadly gone down since radiation from 3.75. I was told again to expect some flucations and most important was the degree and how much. It will go up and down I was told and already knew that from my own research.
Good luck!!
Replies to "@spaceguy Since you have not had radiation treatments you cannot discuss this is your R/O who..."
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Yes, I noted that above, no bike riding, no vigorous exercise, no ejaculation, no DRE before (or after for that matter), and my other bloodwork and urinalysis showed no signs of infection.
That being said, I went back and looked at old data because I have I believe 14 years worth of PSAs. At my former urologists office, he was attached to a medical college, so I always saw a resident or fellow before I saw him. They always asked me all the questions and then performed physicals before I saw the doctor. There were a couple times (confirmed in my records) where they performed DREs the same day they performed PSAs. The bloodwork was always the last thing that happened at this office after I saw the doctor. So it could be 30 to 60 minutes after the DRE. Those readings showed no difference from the one the year before or after. On one of my earliest visits they performed a DRE during the physical portion. I also had to produce a semen sample for analysis. (I do not recall which occurred first of those two) I also had a PSA test at the end of that visit. That reading was about 0.25 higher than the readings before and after. So I wouldn't expect any of that to have a 1.5 ng/ml impact.