Your sed rate and CRP are at a quite high level, indicating chronic inflammation, which you know. The combination of your problems you have experienced certainly points to an autoimmune disorder in the rheumatology family. Lupus and rheumatoid arthritis are the most common diseases. Some people with these conditions are seronegative, meaning the usual blood tests to detect these diseases are negative even though you have the condition
( about 5% in lupus and up to 40% in RA) So the.diagnosis can be made by other means. If a rash occurs, a skin biopsy can diagnose lupus. If urine or kidney function is abnormal a kidney biopsy can diagnose lupus. For RA, xray or MRI of a painful joint might show joint erosions. The inflammation causes cytokine release, which causes the fatigue. Your anemia from inflammation is severe. Under the circumstances, treatment can be given even without a specific diagnosis. Chronic inflammation can cause cardiovascular disease as well. It would seem prudent to discuss with your rheumatologist getting some of these other tests, if appropriate, making sure all blood tests for autoimmune diseases have been done and then asking for treatment, perhaps prednisone initially to see how you respond and feel. The Mayo Clinic would be helpful if you don’t feel your workup has been adequate. I hope you get a diagnosis soon and treatment, as your illness seems rather severe and I believe it is dangerous to let this level of inflammation continue.