rosegarden000
I did have the TP53 mutation. It was found when I had my dbl mastectomy in early 2022. It was noted in my chart, but no action was taken. My genetics profile had already given me Brca2. I had chemo back then, and a drug called Lynparza. My blood numbers were not getting better in August of 2023 after all my treatments ended. I asked my oncologist office to let me see a Hematologist. He looked at my reports, met with me and had me complete a bone marrow biopsy a few weeks later. Ultimately that showed the TP53 and the makings of MDS. Wow! Not yet AML, so I could watch and wait or have a BMT.
I took a couple minutes to think about it. No way was i going to watch and wait. Not everyone will get leukemia, but i did not want to take the chance. There are statistics on MDS and not all is good. What i also know is side effects and statistics are different for every single one of us. My tumor grew fast in my breast and only shrunk half with 13 rounds of chemo.
I got put in the Be a Match system and a 10 out of 10 match was found. My BMT was April 9th of this year. Day 75 from transplant. I had it done at the City of Hope in Duarte California. It was a procedure pretty close to what Mayo does. You will hear about that from someone else I bet. I am sure way more of the research cancer hospitals have transplants with mostly the same procedures. Statistics to say it works.
At 30 days we have a BMB, my donor was nearly 100% of my blood in my marrow. At 100 days I have another to BMB to see how things are looking. So far, the meds i have taken to stop rejection have worked. I have little to no side effects since I left the hospital on April 29th. And, because I had MDS, I did not have leukemia to fight.
More will be revealed.