@happytrails123 Forteo and Tymlos are similar and work through the parathyroid. They are different from Evenity, which inhibits sclerostin, as @gently explained.

Not a single human has gotten cancer/sarcoma on Tymlos or Evenity, and the black box warning has been removed from both. You are not the only one getting info that is old!

Evenity was studied in comparison with placebo for cardiovascular risk and there was no difference. Compared to alendronate, however (Fosamax) it had slightly more risk. There was a theory that this was because alendronate was slightly protective, and another theory that it was due to chance!

I chose Tymlos (adjustable dose) for two years followed by Evenity (I only did 4 months). All of these drugs need to be followed by a bisphosphonate like Reclast or Fosamax to "lock in" gains.

You can read Keith McCormick's book "Great Bones" or watch Dr. Ben Leder's video on YouTube on Combinations and Sequencing but sometimes too much research can be counterproductive 🙂