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Bone Coach - How do you know it works?

Osteoporosis & Bone Health | Last Active: Nov 8 9:44am | Replies (215)
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@leeosteo

Hi karen, could you share any studies you find re hrt for women over 65? I'm 67, on Forteo, and considering hrt as follow up med.

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mayblin | @mayblin | Jun 23 3:16pm

@leeosteo here is one related to hrt timing and cvd risk https://www.nejm.org/doi/full/10.1056/NEJMoa1505241#:~:text=Oral%20estradiol%20therapy%20was%20associated,or%20more%20years%20after%20menopause.

"CONCLUSIONS
Oral estradiol therapy was associated with less progression of subclinical atherosclerosis (measured as CIMT) than was placebo when therapy was initiated within 6 years after menopause but not when it was initiated 10 or more years after menopause. Estradiol had no significant effect on cardiac CT measures of atherosclerosis in either postmenopause stratum"

This is also what my obgyn told me: no cv benefits if hrt initiated 10yr after onset of menopause when compared to hrt therapy initiated closer to pm.

As far as cardiologist is concerned, I'd say you start to get all the necessary labs and tests done with your current cardiologist and be followed closely for a year or two, during which time find another cardiologist who'd be a good candidate for a second opinion. By the time when you finishing up your forteo, you'd know whether or not hrt is suitable for you.

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