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Salvage radiation therapy after radical prostatectomy

Prostate Cancer | Last Active: Nov 13 8:13am | Replies (90)

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@robertmizek

Quick question: I’m currently going through 33 sessions of salvage radiation to the lymph node basin for Gleason 9 with EPE If that sounds familiar. Three weeks down and I’m experiencing substantial fatigue and mild to moderate nausea. I’ve also been on Orgovyx and Zytiga for three months. Did you experience any of this?

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Replies to "Quick question: I’m currently going through 33 sessions of salvage radiation to the lymph node basin..."

The short answer...the fatigue is likely the Orgovx and Zytiga, the nausea more likely the radiation.

Zytiga definitely causes fatigue even if taken with prednisone. My husband has taken it since January 2020 and the fatigue doesn't decrease with time. The nausea is probably the radiation as it is likely close enough to the stomach to cause it. See if your doctor will prescribe oral Zofran, anti-nausea dissolving tablets. Those helped when taken just before radiation and also after nausea starts.