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@johnbishop

I'm guessing we are all a little different but here's what I found on your question while you wait for members with experience to respond.

"Official answer. After taking a dose of a Methylprednisolone tablet it should be out of your system after approximately 13 to 20 hours. Methylprednisolone tablets have an elimination half-life of approximately 2.5 hours to 3.5 hours. This is the time it takes for the drug levels in your plasma to reduce by half."
-- How long does methylprednisolone tablets stay in your system?: https://www.drugs.com/medical-answers/how-long-does-methylprednisolone-stay-in-your-177237/

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Replies to "I'm guessing we are all a little different but here's what I found on your question..."

Thank you. I never knew that. So maybe then I should take my dose much later or very, very early a.m. so that it remains in my system later the next day. Reason I take at night is so that I am not stiff upon waking in a.m. to feed and walk our dog.