Can we talk about boobs please? Man Boobs. ADT induced gynecomastia.
I ended a 24 weeks of ADT (Orgovyx and Erleada) on Aug.28 2023. About 12 weeks into the treatment I had lost about 70% of my body hair and my chest had started to enlarge. I knew that this was a potential side effect and mentioned it to my Oncologist's Nurse Practitioner and the nurse who over the drug study I was in at the time. I also mentioned that one side was bigger than the other. They both laughed and said "join the club". I said that I had read that one of the side effects could be sensitive breasts, but that my breasts weren't sensitive but that I was started to get sensitive about my breasts. We all laughed. Now 4 months later and no longer on ADT my breasts are about 4 times the size they were before I started ADT. Luckily I was always rather flat chested but I am concerned that they will continue to grow when I resume ADT. I would love to hear what others experiences have been with this rather sensitive topic. And yes now my nipples are very sensitive (sore to the touch).
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@aldenrobert
Having had this embarrassing thing is something that has bothered me for decades. I tend to have fat accululate in the breast area and very embarrasing. I know weight loss would help but went through proton radiation treatment in 2023 and gain a lot of weight because had reverted to eating a lot of comfort food.
I then was having some issues with my heart failure and my HFD put me on a drug that made my breast swell, hurt especially my nipples. I read up about it and sure enough the side affects of this drug causes them. Just what I needed more, bigger breast. He changed my medication that has a lot less side affects.
I just don't want anymore radiation and the heart medications I am on is important. I read your post and you have an outstanding doctor, ton of experience and a caring one. That is hard to find this days.
jc76, Thank you for your reply.
Forums like this are so important for patients. We are our own best advocates for our healthcare. Hearing from others that have had similar treatments and their side effects helps us to initiate conversations with our care team and make informed decisions.
3.6 Years in. Just went from XXL t-shirts to XXXL. Pants are getting tight, come fall I'll need to go up another size. Makes no sense. I am eating better, much better and less. I am exercising more, much more than ever before. Makes no sense in terms of my pre-advanced prostate cancer life. But, in my new advanced prostate cancer life it's the price of admissions. 120 to 180 minutes a day of mild to moderate exercise. All four types; endurance, strength, balance, and flexibility exercise every week. 2-3 Nutritional based meals per day. Results, outside of my enlargements I am living my best version of self-level. Keep trying!
Surgery for that shouldn’t be a big deal, right? I mean, compared to robotic prostate removal. They probably liposuction the accumulated fat out. Don’t want to be flip but I DO know where I’d put it!😁
This thread is just one of the MANY reasons i chose an orchiectomy with reconstruction (implants).
We have enough to deal with without adding to it.
My heart goes out to you guys.
PS: Just so you now, you can always switch from the chemical approach to the surgical solution.
Best Regards
Gynecomastia is common for both chemical castration (lupron et al) AND orchiectomy. It is caused be the lack of testosterone which both approaches cause.
There are treatments that can help with gynecomastia. One option is a couple of shots of radiation to the breasts (see a radiation oncologist). The other is a drug called tamoxifen. These options cannot reverse breast growth but they can arrest it.
You are correct.
I just had three rounds of radiation to my breasts to prevent further growth when ADT resumes.
My situation is I had radiation to a lymph node on my right lung. That radiation had the side effect of reduced breast growth of my right breast. If I did nothing my left breast would have grown much larger than my right one when the ADT started back up.
We shall see.
i am on month 3 post orchiectomy and no change.
Only time will tell.
I wish you the very best.
My enlargement started about four months into the ADT treatment and continued for a couple months after stopping the treatment. Knowing that I would be resuming ADT after a "treatment holiday" and that the side effects can be cumulative I decided to have the three short rounds of radiation to prevent the Gynecomastia from continuing.