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Forteo: What is your Experience?

Osteoporosis & Bone Health | Last Active: Jun 22 6:52am | Replies (67)

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@loriesco

@gently THANK YOU. Also, I was really curious about the "short breaks." I hate to tell you how "not-up-to-date" my endocrinologists are but they are lousy at providing support. I have an intuition that I might want - or need - to take breaks. I do some physical work and I am concerned that I won't have the stamina/energy to do the work I need to accomplish. So I was thinking about a break. I took one in March - no, let me rephrase - I waited until after my 5K walk 3/10/24 to get started. I felt loopy so it was good that I waited. I did 3/20 - 4/20. Then I waited again until I could speak to the nurse. It seems like they just read the info off the insert! I've been slowly reading comments here and it seems like others slowly ramp up (I am at 6 clicks now) and I was considering breaks if I can't get focused. All of a sudden, I am getting more clear headed. I switched to evening injections. I did a reclast injection July 2023. Had a HORRID reaction. So I was put on this. I was told to do this for 2 years then go back to the reclast (I think it was 3 annual injections) and I would be done for life.
They didn't do any blood tests to start me on the Tymlos. I ASKED for some when I saw calcium, D, , etc should be tested. I always got DEXAs but when my bones fell apart in surgery my surgeon said don't bother my wrist doesn't tell anything - to vague. (my bigger joints were replaced). My wrists were normal. Is there some bone markers you can point me to to educate myself? Any info on the "short breaks?" (I did bring this up as an idea if I couldn't get rid of the side effects and they poo-pooed it. I'm also wondering - since I am a petite person if I might want to stay at 6 clicks. I mean, would a 280 pound male do 8 clicks and a 5'2" 140 petite woman do the same? Thank you!

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Replies to "@gently THANK YOU. Also, I was really curious about the "short breaks." I hate to tell..."

@loriesco
Bone markers CTX and P1NP are best used to determine if a medication is effective. CTX measures the activity of osteoclasts; P1NP measures the activity of osteoblasts. I'd be curious to see those markers now because Reclast which is active for a year or two, clads the bone preventing the attachment of both types of cells to a gradually lessening extent for ten years.
Interesting you were told you would be "done for life."
Where are you receiving treatment.
Would you say that you are getting more focused because you've adjusted to 6 clicks.
Was the horrid reclast reaction longer than a week. It would be usual for you to have benefit from reclast despite the adverse response.
I agree with you about titrating for size. I harbor the suspicion that even one click would hold some advantage. I hope Windyshore's weighs in with expertise and a firmer concept about dosing.