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Forteo: What is your Experience?

Osteoporosis & Bone Health | Last Active: Jul 20 9:29am | Replies (97)

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@gently

@loriesco
You didn't miss anything. Sorry.
https://www.drugdiscoverytrends.com/fda-approves-removal-of-boxed-warning-from-label-for-osteoporosis-drug-tymlos/
Maximum dosage has changed. Protocal will be slower, as always. The internet has all kinds of outdated material. You'd expect the drug inserts would be updated. The university websites are particularly egregious and they often don't even cite study sources
Too many osteoporosis providers are unaware of the changes and too many don't know how to use bone markers, which I think will be crucial to the understanding of long term Forteo and Tymlos use in individual patients.
The issue is (no longer bone cancer) the anabolic window. At some point on PTH meds the osteoclasts catch up to the osteoblasts because more osteoblastic activitiy stimulates the osteoclasts. Short breaks from Tymlos or Forteo may be the solution.

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Replies to "@loriesco You didn't miss anything. Sorry. https://www.drugdiscoverytrends.com/fda-approves-removal-of-boxed-warning-from-label-for-osteoporosis-drug-tymlos/ Maximum dosage has changed. Protocal will be slower, as..."

@gently THANK YOU. Also, I was really curious about the "short breaks." I hate to tell you how "not-up-to-date" my endocrinologists are but they are lousy at providing support. I have an intuition that I might want - or need - to take breaks. I do some physical work and I am concerned that I won't have the stamina/energy to do the work I need to accomplish. So I was thinking about a break. I took one in March - no, let me rephrase - I waited until after my 5K walk 3/10/24 to get started. I felt loopy so it was good that I waited. I did 3/20 - 4/20. Then I waited again until I could speak to the nurse. It seems like they just read the info off the insert! I've been slowly reading comments here and it seems like others slowly ramp up (I am at 6 clicks now) and I was considering breaks if I can't get focused. All of a sudden, I am getting more clear headed. I switched to evening injections. I did a reclast injection July 2023. Had a HORRID reaction. So I was put on this. I was told to do this for 2 years then go back to the reclast (I think it was 3 annual injections) and I would be done for life.
They didn't do any blood tests to start me on the Tymlos. I ASKED for some when I saw calcium, D, , etc should be tested. I always got DEXAs but when my bones fell apart in surgery my surgeon said don't bother my wrist doesn't tell anything - to vague. (my bigger joints were replaced). My wrists were normal. Is there some bone markers you can point me to to educate myself? Any info on the "short breaks?" (I did bring this up as an idea if I couldn't get rid of the side effects and they poo-pooed it. I'm also wondering - since I am a petite person if I might want to stay at 6 clicks. I mean, would a 280 pound male do 8 clicks and a 5'2" 140 petite woman do the same? Thank you!