My personal research (not intended as advice) indicates that Vitamin D3 along with Vitamin K2 (M-7) synergisticly helps the calcium to be used by the bones and thus, reduce the amount available to calcify your arteries. My CAC score has increased from 378 to 798 in 4 years. Thus, I have shifted to a plant based diet along with some selected seafood like salmon. In on month, my cholesterol when down to desired levels along with the statins I have been taking for over 30 years. However, my Lipoprotein a is over the top at 289. To reduce these risks, I hope to keep my High Sensitivity C-Reactive Protein level below 2 mg/mL. I am currently at 0.26. Inflammation and a healthy lifestyle is apparently very important to manage heart disease. I am 79 and still very active and overall very healthy. The key is to make the best of each day knowing they are limited and a gift.