I just watched a Paul Miller video and he does say Prolia can be taken long term, even forever. Depending on monitoring. The risk of atypical fractures with Prolia is much less than with bisphosphonates, he said.

If I were on Prolia I would have contradictory feelings. On the one hand, if Prolia is taken for a year or two, there are gains and the rebound can be addressed with Reclast or even alendronate.

The longer Prolia is taken, the worse the rebound so after 3 years it seems we would be kind of trapped into doing it long term. For some that is an answer though.

For those experiencing side effects, this is all moot.

My docs don't use Prolia unless they have to but various videos do have some things to say about its effectiveness.