I had been taking 1,000mg of curcumin/turmeric each day to see if it helped with PMR symptoms. I had tapered Prednisone from 20mg per day to 2,5mg but had flare up because of almost 2 weeks of continuous stress. Not wanting to go up on the medicine, I decided to try various other methods to relieve nightly pain and daily fatigue. Yesterday I increased Turmeric to 3,000mg daily, this morning I have stiffness, but no debilitating pain. Of course I really don't know if this is because of the increased Turmeric, however, I plan to continue with the increased dosage.