Unfortunately not great. I will be creating a new thread as well but no change in colon tumor, pelvic one is a bit smaller but there are multiple new mets on the liver that continue to grow. Lab work yesterday showed CEA shot up 182 in the last 2 weeks now at 547. We have discontinued IV chemo as the side effects are either too bad or they are no longer effective. We are waiting on Lonsurf (chemo pills) to be approved by insurance and will then start that. It was going to be a combo of lonsurf and Avastin but the Avastin is causing bad side effects again (nausea, loss of appetite, weight loss, kidney issues among other things).