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Anyone experience severe side effects increasing Bupronion dosage.
Depression & Anxiety | Last Active: Jun 24 8:51am | Replies (29)Comment receiving replies
I’ve been taking 150mg Bupropion for 4 months. Increased to 300mg a few days ago, and not for me. I was so jittery, and felt anxious. My HR increase and just overall felt wired. The 150mg didn’t have such an affect but in the beginning was slightly stimulating. With the 150mg I felt a good amount of normal energy throughout the day with no extreme highs or lows. I wouldn’t say I felt “motivated” to do things I needed to do, but I oddly I just did the things I needed to do, i.e. gym, clean, stay at work to complete a task. Was I happy and motivated to do these task? Nope, but I just did them anyway. I’m still trying to understand that. It’s helped for those things in life. It sounds like you’re having the opposite effect unfortunately. I wish we could get a test on what neurotransmitters we are deficient in so we know what meds work effectively, or at the very least know if we need a SSRI, SNRI or NDRI. I don’t want to treat something I’m not deficient in because that could do more harm than good. This is just my experience, I hope your symptoms get better and if not there’s other options out there. Best of luck to you!
Replies to "I’ve been taking 150mg Bupropion for 4 months. Increased to 300mg a few days ago, and..."
I have been on and off bupropion for years, was not able to take other antidepressants I tried (I’m now 80 so I’ve had depression most of my adult life). I’ve been on 300 mg for some time. Periodically I feel very agitated and still depressed- discussed changing w my provider but based on my history she thinks I should stay w this. I have found that different generics affect me greatly and have found a small private pharmacy that will continue to order the one generic that seems to work best. CVS/Walgreens etc only gets what the company orders in bulk. I hate this whole thing and sometimes think I might have been better off not to be on any but I think my system has adapted to needing it. Withdrawal is VERY scary and agitating for me even gradually. And I do think it affects my heart rate. Since I have AFib and other heart issues I worry it affects that. I do believe that Years on antidepressants affect your brain chemistry. I feel too old and have other health issues so I just bumble along. (Wow. That sure sounds like I’m depressed doesn’t it?). Very few practitioners in my area and mental health services almost a joke!
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Thank you for your good wishes. I feel exactly the same about over medicating. Suspect I am currently suffering RLS and am dependent on Pramipexole caused by decades of SSRIs.
I have tried to educate myself re Bupronion and found patients with many different experiences, mostly with the 300mg. My experience with the 150g is very similar to yours. I am concerned that my PCP wants me to maintain Fluoxetine 10mg along with Bruponion 150g but I am working on that, onwards and upwards!!