I’ve been down a similar road. Started 12 yrs ago on Humira and Methotrexate (after the required step drugs that don't work but are cheap). Methotrexate made my liver enzymes go up and up but when we lowered it enough to stop that, it no longer prevented me from developing antibodies to Humira. So my doc switched me to Enbrel. Liver enzymes stayed above normal so I switched to subcutaneous injection. But finally we switched to infusions of Remicade four years ago. Its great. I’m well controlled with no material side effects other than fatigue from time to time.
But if feels like its just not working as well as he decreases Methotrexate, ask if an antibody blood test should be considered.

Good luck…