I have Connective Tissue Disease and Fibromyalgia. I have pain every day. I've used 5/5 THC with CBD before bedtime and it helps me. I might be due to the body relaxing effect of that combo. The THC helps the CBD reach the desired transmitters to have an effect. For me the 10 mg 10/10 (1/2 THC 1/2 CBD per dose) edibles make me feel too high. If you try this, I'd suggest taking only one 1/2 dose to see how it affects you. And of course ask your Doctor's opinion regarding your medication and kidney status first.