Lots of discussion on this thread to MTX. Generally the idea is to shut down your immune system as much as possible to allow you to get off the steroids. I find it pretty interesting you were able to make off it without any pain. Hydroxychloroquine and Methotrexate are both RA type drugs to do just that shut down your immune. Doing that also leaves you susceptible to may types of infections, viruses, eye problems, etc. The goal is to get you off steroids. Provided you dont have anything else going on. Having one autoimmune disease seems to open the door. However many on here say they dont work for PMR. In your case they worked. The issue is usually tapering off of steroids that creates new inflammation and can restart the PMR. I would think your goal and your Dr's would be to get the PMR under control to get off prednisone and then discontinue the other drugs. Taking both drugs your body is not able to respond to any kind of an immune threat. Right now you need to get PMR under control. But these drugs dont necessarily prevent PMR. They have some newer drugs that may help. Kevzara and Actemra.