Very sorry to hear about the diagnosis. I would say positivity and encouragement are among the first things you could provide. Every statistic on Google and in medical literature is from data that is now several years old, and the statistics are only getting better as the drugs and treatments get better. I've been Stage-4 PDAC now for about 1.5 years, with no ill effects from the cancer. Chemo has not been fun, but it has kept the disease under control all that time with only 2-3 "down" days immediately after my treatment every two weeks. Others here and elsewhere have survived and lived healthy lives even longer at Stage 4. Everyone is different, and everyone responds differently to treatment, but there is hope!

It is also reassuring to feel confident your (her) doctors know what they're doing, so patients feel like they are getting the best care available. Sometimes you have to go through the "Level 1, Standard of Care" treatments before you get to the newer, more advanced stuff. If her doctors aren't experts in pancreatic cancer or affiliated with a large, high-volume research institution or center of excellence, you might want to see if she can get into one. Sometimes you can get the doctor at a top-notch faraway institution (Mayo, Anderson, Sloan, Hopkins, etc) to direct your care and have it provided locally by hometown doctors. That provides a good second opinion on things and shortens the path to clinical trials provided by that institution.

Although it's circular logic, staying in shape helps you stay in shape. Don't let the burden of cancer disrupt her physical activity or nutrition. Avoiding the slippery slope to a downward spiral will improve overall quality of life and preserve the "performance status" (overall health) needed for entry into many clinical trials.