I had sky high urine calcium on Tymlos but normal serum calcium.

Tymlos prescription information highlights high RCA Calcium scores as a Known, Serious Side-Effect in some patients. Nowhere does the prescription information mention that this serious side-effect is temporary in those patients. I did not have a high RCA Calcium score before taking Tymlos. I had been taking Tymlos for 18-24 months before my latest RCA Calcium score, which was above 300! I took Tymlos nightly before bed. My RCA Calcium score was measured on a weekday afternoon, 13 hours after my prior dose of Tymlos, so if its effect on RCA Calcium is short-lived (which is not referenced in any of the drug's literature), it had more than enough time to dissipate. I've never been over-weight, eat a very healthy diet and rotate both cardio and strength training at least 5 days/week. My Bone Specialist should have been monitoring my calcium levels, but didn't. Fortunately, my GP does. High Calcium scores can be present and people often don't know it. In my case, my Blood Pressure was normal and I had a low resting heart rate (in the 40's). My RCA Calcium score put me at a 5X greater risk for a heart attack, or stroke within a 5-year period and the only way I found out was thanks to my first-class GP and concierge physician. I contributed my post in the hope that other people taking Tymlos will make sure that their Bone Specialist monitors their RCA Calcium levels, or will request that their GP do it. I have stopped taking Tymlos and will be following up with my GP to determine when we will want to take my RCA Calcium levels again. My GP has also referred me to a new bone specialist.