@spongybob , You're very welcome! Good attitude and fully understood.

Did you find a section in your post-op pathology report or get word from your surgeon on what the tumor response score actually was? They would probably only even consider something similar to Folfirinox if your response score was good. If it was, and no better options are immediately available, you might inquire if the Leucovorin + 5FU (the sucky part being the 46-hour pump you take home) could be replaced by oral Capecitabine (which converts to 5FU in your system). Since you were hospitalized 3 times, that is not a good sign for the Folfirinox-related options/ingredients. With the GAC, you might still ask about starting slow (lower dose) to avoid bad reactions and determine sensitivity to each drug individually. There was a trial at Mayo/Jax (possibly other locations) adding TTF (Tumor Treatment Fields) equipment to GAC for patients with liver mets. Not sure if it's still recruiting or is available at a realistic location for you, but you would have to get into it all at once (before starting chemo) to qualify.

Here's hoping the chemo bridge is short (if you even have to cross it) before getting to a longer-term solution via a more tolerable trial drug/therapy.