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PMR pain management with medical cannabis

Polymyalgia Rheumatica (PMR) | Last Active: Oct 23 11:39am | Replies (56)
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@dadcue

"At present I'm taking methotrexate, prednisone, duloxatine and lyrica. With minimal relief."

I remember taking all those medications but not all of them at the same time. I probably relied on prednisone too much because I took very high doses of prednisone for a very long time.

I can only imagine what PMR on top of RA is like.

I had PMR on top of reactive arthritis (ReA) so I imagine the combination of PMR and RA is not good.

I don't have any experience with CBD oil and PEA. Now I only do a monthly infusion of a biologic called Actemra (tocilizumab). I don't seem to need prednisone anymore or any other pain medications except maybe Tylenol (acetaminophen) once in a while.

Have you ever tried a biologic to treat RA? There are many biologics suitable for RA.

There aren't too many biologics for PMR but that is beginning to change. There is one biologic called Kevzara (sarilumab) that is FDA approved for both RA and PMR.
https://rheumatology.org/patients/sarilumab-kevzara

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Replies to ""At present I'm taking methotrexate, prednisone, duloxatine and lyrica. With minimal relief." I remember taking all..."
jacquianddan | @jacquianddan | Jun 8 6:22pm

Forgot to mention I'm on Rinvoq (upadacitinib as hemihydrate) 15 mg which seems to have my RA well controlled. PMA isn't mentioned as one of the conditions it is recommended for. Haven't heard of Kevzara but it could be marketed under a different name in Australia. Have been through all the other biologicals, one of which left me with peripheral neuropathy.
Rinvoq is a Janus kinase (JAK) inhibitor. Works inside cells to block certain signals thought to cause inflammation.

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