Welcome @ruth1942, I moved your question about golimumab (Simponi Aria®) and living with the pain of ankylosing spondylitis to this active discussion:

Ankylosing spondylitis: anyone else?
https://connect.mayoclinic.org/discussion/ankylosing-spondylitis/

I did this to help you connect with fellow AS members like @candybeason45 @kelsey1 @kavardell @velvmex and others.

Ruth, how long have you been taking the infusions?

Hi, Ruth,
Are the infusions helping? I have axial spondylitis and have ankylosing at one level currently. I also have ligaments that have hardened which is another symptom of ankylosing spondylitis.

I currently use Enbrel, a biologic, once a week. I was diagnosed two years ago but have been suffering from AS and psoriatic arthritis for around 35 years. I do have lots of experience and medical knowledge of our disease.

My AS has been very active over the past 7-8 months. My rheumatologist is struggling to find the right biologic for me. In the meantime, my hips, especially the left one, SI joints and low back are really flared up. I seem to have new damage but we'll see for sure when I have my next MRI. Like you, I'm having more bad days then good.

I usually have good mornings once I get moving. But after a while, my back muscles get so tired and stiff from all the inflammation. I always have to get out my heating pad in the early afternoons.

I'm currently also doing physical therapy and I've joined a pool class for people with arthritis that runs on Tuesdays and Thursdays.

I hope you are having one of the good days.