I was nervous about giving myself shots when I started on Tymlos almost 2 years ago but it's not as bad as it sounds. The trick is to "pinch an inch" of belly fat, then push needle in and depress the plunger part. Real quick--and the needle tip is very small, thank goodness! I went to my doctors office for the first time so she could walk me through it. Maybe you could do that? I also take mine right before bedtime because it tends to make me sleepy. Tymlos will help you build up some bone--while prolia will only hold on to what you have right now. My spine has showed a 12% improvement after 18 months on Tymlos. Good luck!