Xifaxan for SIBO

Sorry, no success story from me. I tested positive, "off the chart" with SIBO and I think I've been suffering from birth with it. But the Xifaxan (which cost me $1,900) didn't work for me at all. (The Florastor didn't work either.) As I heard someone here on this site say, the Xifaxan doesn't get at the cause of the SIBO so it comes right back as soon as you stop the Xifaxan. And last I heard, they still don't know what causes the SIBO, so no wonder there doesn't seem to be a cure for it.

I need to hear some success stories. Everything I've read on the internet shows very poor efficacy of Xifaxan. My doctor has order 550 mg twice a day for 14 days along with Neomycin. Both are antibiotics. The Xifaxan is going to cost me $1,057.73. Also, I've read Xifaxan can cause C. Diff. (hospital acquired from spinal surgery) and after 3 years, I am still recovering from the damage that nasty bacteria left in my colon.

I'm sorry it didn't help you. The first time I took Xifaxan, it improved my symptoms slightly, but I didn't have complete resolution.

It turned out I had methane-dominant SIBO and for methane-dominant SIBO, they've found that Xifaxan + Neomycin (another antibiotic) is more effective. Did your breath test indicate what type of SIBO you had?

It's so frustrating.

Yes, the test showed both methane and hydrogen. My doctor called in both Xifaxan and Neomycin. He also said I could look up SIBO diet on Dr. Google. Thank you to emo too. Good to know I may need to take the Neomycin with food. Keeping my fingers crossed.

I need to hear some success stories. Everything I've read on the internet shows very poor efficacy of Xifaxan. My doctor has order 550 mg twice a day for 14 days along with Neomycin. Both are antibiotics. The Xifaxan is going to cost me $1,057.73. Also, I've read Xifaxan can cause C. Diff. (hospital acquired from spinal surgery) and after 3 years, I am still recovering from the damage that nasty bacteria left in my colon.

Sorry, no success story from me. I tested positive, "off the chart" with SIBO and I think I've been suffering from birth with it. But the Xifaxan (which cost me $1,900) didn't work for me at all. (The Florastor didn't work either.) As I heard someone here on this site say, the Xifaxan doesn't get at the cause of the SIBO so it comes right back as soon as you stop the Xifaxan. And last I heard, they still don't know what causes the SIBO, so no wonder there doesn't seem to be a cure for it.

h8bigbiz. We're so different and treatment is as well. I took Xifaxan for ??IBS (my diagnosis) and it worked great. A year of so later my symptoms ramped up so I was prescribed Xifaxan again but it did not work as it did before. Later on I had another colonoscopy and my GI doc did multiple biopsies throughout my colon which revealed microscopic colitis. I was ordered Budesonide for 3 months. Results was amazing. All was great and then a year later the diarrhea plagued me again--5-6 trips to the bathroom every day. I just finished the 3 months last week. The good results came within a couple of days and continues now. If I had to go through the treatment every year or two, it is well worth it. Good luck.

h8bigbiz. We're so different and treatment is as well. I took Xifaxan for ??IBS (my diagnosis) and it worked great. A year of so later my symptoms ramped up so I was prescribed Xifaxan again but it did not work as it did before. Later on I had another colonoscopy and my GI doc did multiple biopsies throughout my colon which revealed microscopic colitis. I was ordered Budesonide for 3 months. Results was amazing. All was great and then a year later the diarrhea plagued me again--5-6 trips to the bathroom every day. I just finished the 3 months last week. The good results came within a couple of days and continues now. If I had to go through the treatment every year or two, it is well worth it. Good luck.

Xifaxan is a treatment for symptoms of SIBO. Every time I went off it, my symptoms returned. It’s not enough to take any pharmaceuticals or natural supplements without also changing your diet. My doctor has a dietitian that helped with kinds of foods to eliminate for a period of time to be reintroduced later one at a time until my gut healed.
There’s also a great book - SUPER GUT - you can order on Amazon that’s really helpful on foods that are gut healing, includes easy recipes. It’s worth checking out.

I need to hear some success stories. Everything I've read on the internet shows very poor efficacy of Xifaxan. My doctor has order 550 mg twice a day for 14 days along with Neomycin. Both are antibiotics. The Xifaxan is going to cost me $1,057.73. Also, I've read Xifaxan can cause C. Diff. (hospital acquired from spinal surgery) and after 3 years, I am still recovering from the damage that nasty bacteria left in my colon.