← Return to Has anyone taken the targeted therapy osimertinib (Tagrisso)?

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The steroid pack just finished and was extremely helpful. His appetite is coming back and his cough and energy level is improved. Tagrisso is approved for his EGFR marker following surgery and two rounds of chemo. His doctor is waiting for tests and improvement after chemo. He received the tagrisso pills and reviewed the side effects. He's scared. Any advice?

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Replies to "The steroid pack just finished and was extremely helpful. His appetite is coming back and his..."

I took the 80mg everyday same time for a little over a month. I couldn’t handle the side effects which included fatigue, occasional diarrhea, skin dryness, itchiness, and almost constant mild headache. My oncologist dropped me to one 80mg pill every other day and I feel so much better. The side effects do come back on the day I take the pill but overall I’m much better. I’m stage 1b cancer with no Mets and an upper lobectomy a 3.5 months ago. So the Tagrisso is purely to help stop any cancer returning. I hope the lower frequency works 🙏🙏🙏….Stay strong !!

@carrmb, remember that the list of side effects has be incredibly exhaustive as we are one of the most litigious society's in the world. What's important are the side effects his oncologist tells him about. After all, every body is different.

Seems we all start with the diarrhea, but that passes (No pun intended.) after a few months. Skin rashes are somewhat common -- see a dermatologist. Nail splitting is corrected by Biotin - I take 20 mg/daily, but be sure to check with your oncologist before adding any meds. Overall, I and several people I know have been on Tagrisso for years with no or minimal recurrence. Have hope!