@petr - Oh boy, did you bring up a subject that everyone with PN has thought about more than once. I'm a few years younger than you with now 9 years since diagnosed but it likely started well before 2015. Unfortunately, this disease has more questions to it than answers. That is the problem. With idiopathic, the medical community can tell us what we have but not why. As far as the future? Everyone with PN is different so no hard to predict but my wife and I plan ahead and figure out how to do it one way or another. We may need to make changes on how we do things now as compared to how we did the same things before which for me is OK. Be well, keep moving. Ed