I was diagnosed with stage 4 colo-rectal cancer in 2021. Spread to my liver, I have nodules on my lungs but they didn't grow or change until recently. It's a HARD battle! Hopefully, he isn't underweight going into chemo. I was already severely malnourished, so that was hard. But... what helped me with all the chemo meds (the take-home pump especially) and insomnia is medic. marijuana. It helped with everything. I've had (I think) 14 rounds of chemo, 4 rounds of proton radiation (SOOOO COOL), and 3 major surgeries and about 7 small ones and ablations. I honestly feel pretty good most days, considering... Good luck to your brother and you stay strong too! I've watched people I love burn out trying to keep up and handle it all.