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@bboeshore

Potential New Treatment for "Brain Fog" in Long Covid Patients by Isabella Backman. This was released by Yale School of Medicine and involves taking 600mg of NAC which is an OTC and starting with 1 mg Guanfacine which is a prescription ADHD drug also used for many things including traumatic brain injury. I've had the brain fog since March of 2020. I've been using the NAC for two weeks now and it is helping and will have my doctor prescribe the Guanfacine. The doctor, Arman Fwaharaki-Zadeh,MD PhD, who treats patients with traumatic brain injury tried this on Long-Covid patients and authored this article. It is a must read article. I've also read an article on the use of low-dose Naltrexone and its positive effect on LC.

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Replies to "Potential New Treatment for "Brain Fog" in Long Covid Patients by Isabella Backman. This was released..."

Thanks for sharing. I’ve also come across this article and wondered about the NAC. I’m nervous about stronger medications because I’m so sensitive to them (like the stimulant guanfacine) but good to know you’ve had a positive response with the NAC.

I started taking this combination on Dec 24th 2022. I woke up Christmas morning and wept because it was the first time in two years that I wanted to get up and just engage in life. It hasn’t fixed everything but the difference has been amazing.

Guanfacine is not a stimulant. In fact, it lowers blood pressure (which is an added benefit for me). I have also been taking a stimulant (Vyvanse) since early 2021, but after starting on Guanfacine I’ve lowered the stimulant dose to half what it was before. The combination has made it so I no longer worry about being able to continue working, and I can work full days without crashing.

I had tried NAC for a while before I started with Guanfacine and didn’t notice any real difference. I am taking it now as described in the article. I am up to 3mg Guanfacine, but unless you have high blood pressure that might cause dizziness.