← Return to Prednisone for over a year along with Kevzara for last 5 months

Discussion
Comment receiving replies
@suetex

Has anyone had the IL6 blood test and found it useful? Tell me your experience.

Jump to this post


Replies to "Has anyone had the IL6 blood test and found it useful? Tell me your experience."

I never had my IL-6 level checked. However, I'm taking a medication that inhibits the IL-6 cytokine and stopped my chronic inflammation and relieved my pain after 12 years of PMR treated with Prednisone. . I assume my IL-6 level was elevated but now it is reduced by the biologic I take that inhibits the IL-6 cytokine.

Actually the biologic probably caused my IL-6 level to rise rapidly at first before my IL-6 level returned to normal.

Nobody knows exactly how IL-6 inhibition works but it seems to stop my PMR symptoms and allowed me to taper off prednisone.

A theoretical diagram of how Actemra (tocilizumab) works is seen in the following link.

https://www.researchgate.net/figure/Mechanism-of-action-of-tocilizumab-in-RA-bathtub-theory_fig2_221967570

I'm proud to say it only took me a few weeks to understand this diagram. I don't know why my IL-6 level wasn't checked first before starting Actemra.

The same mechanism should be applicable to Kevzara. Here is another great link that I won't take credit for because someone else posted it first.

https://www.pmrandil6.com/il-6-and-pmr/