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Side effects from Zoledronic Acid?

Osteoporosis & Bone Health | Last Active: Aug 5 2:48pm | Replies (20)

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@michaellavacot

Hi @jo2184 - My guess is that moving from alendronate after 3.5 years to Reclast is not going to help your hip gain much if any BMD. They are both bisphosphonates with basically the same action. Both drugs stop gaining BMD in the hip after about 3 to 4 years. Attached are two graphs from the main trials showing BMD gains.

Depending on what your T-scores are now and where you want them to be, you might consider an osteoanabolic like Evenity or potentially Prolia.

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Replies to "Hi @jo2184 - My guess is that moving from alendronate after 3.5 years to Reclast is..."

I appreciate your extremely helpful response.