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Anyone have discomfort or pain when tapering off prednisone?

Polymyalgia Rheumatica (PMR) | Last Active: Sep 22 7:45pm | Replies (144)
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@besmith57

I had my blood work done yesterday. Some markers are still off. My doctor is going to put me on Kevzara after being approved. The kevzara scares me My dr. called me yesterday to tell me because I have diverticulosis I could have digestive or bowel issues. I have never had any symptoms of diverticulosis. Has anyone had an issue with this drug? I also take 12 mg methotrexate. I love this site for its information.

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Replies to "I had my blood work done yesterday. Some markers are still off. My doctor is going..."
linda7 | @linda7 | Jun 2 6:20pm

I just started on Kevzara. I did my research on it including reading the report of the phase 3 clinical trials. Yes, there is a rare side effect of the bowel which my rheumatologist explained to me. I don't have any known bowel issues. I also had to have a special test for tuberculosis. The drug hasn't been around very long and it does affect the immune system so there could be a cancer risk. This is all explained in the drug literature. I decided that it was worth the low known risk. I have been on prednisone over 2.5 years. Methotrexate initially helped me to reduce my prednisone but then did not seem to help and I had side effects, including elevated liver enzymes. I also did not like the way the methotrexate made me feel. I was taken off the MTX as soon as I started the Kevzara. I feel a lot more "normal" after 11 days on the K. I'm glad to be off the MTX. So far, so good. Will report back if I have problems.

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