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DiscussionAre painful swollen hands and fingers a PMR flare?
Polymyalgia Rheumatica (PMR) | Last Active: Jul 4 1:54pm | Replies (158)Comment receiving replies
Replies to "So my sed rate 60 and crp 87 were elevated. RF, ANA, anti-ccp negative. I seemed..."
I don't think its a matter of something you're lacking. It seems to be more like a stuck switch. Your immune system begins to react to something - a virus or allergen or bacteria or such and something triggers that immune process to dial it up - and it doesn't get a signal to stop. So now your immune process is in overdrive and the mechanism to slow it down is stuck.
They don't understand fully what triggered that malfunction - but they have figured out how to stop and in many cases to prevent it - mostly.