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Pancreatic Cancer | Last Active: 3 hours ago | Replies (1500)Comment receiving replies
Can also research the POLO trial which was a research trial of PARP which seems to be the trial which got FDA approval for the drug. This is a scientific paper describing the trial. Give a try at reading it and then try searching POLO trial on Google, might come up with something else.
https://www.nejm.org/doi/full/10.1056/nejmoa1903387
Replies to "Can also research the POLO trial which was a research trial of PARP which seems to..."
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Thank you!
That’s weird: at the mid-trial evaluation you linked to the Overall Survival showed no benefit, though “progression-free” time was distinctly extended. Checking the 2022 followup report after the full trial… the same result held. One would think a discussion of the placebo-identical Overall Survival would have been included, but nope.
[https://snucm.elsevierpure.com/en/publications/overall-survival-results-from-the-polo-trial-a-phase-iii-study-of ]
Scratching my head. I’ll definitely ask my oncologist what this means!