My cardiologist and PCP has me taking a prescription 81 mg. coated aspirin once a day. I was taking regular OTC aspirin. I think this changed (can't remember) when I had a scope done on my stomach and showed some issues associated with those who take aspirin long term (for some not all). I think that is when I was put on the prescription 81 mg coated aspirin.

I asked the pharmacist at CVS about is the prescription for aspirin better than OTC aspirin. I was told yes it has a better coating on it to reduce stomach upset and issues with aspirin and stomach issues taking aspirin. Fine with me the prescription cost at CVS for it is free, no co-pay, where I pay for OTC aspirin.

I do notice that I bleed a lot easier when I started taking aspirin. But I was also told that fish oil can cause that also. I am given instructions on taking all medications and supplement prior to my surgery procedures. Sometimes they decide to stop the aspirin prior to procedure or keep taking it. I lleave it up to my medical specialist to decide. I do know they want you (when they do say stop) up to 2 weeks prior to some surgery procedures I have had.