Pregabalin is my miracle drug. Take one about “dark thirty” ( it’s such a mystery that my pain can tell time). I take another about 9:30 and lately I have not had a lot of nighttime spasms. I have a very rare disease called arachnoiditis. Without a doubt, there are people on this site who have it and have no idea. I have yet to find a doctor in Louisiana who has even heard of it. I was diagnosed at Duke. Currently there is no cure and no real treatment plan.