I hesitate to bring this into the conversation (I am really hesitant) ... But .....
While the medical community from 3,000 years ago can't identify what hormone does what, is can assist in a certain amount cases (at least for mine).
Acupuncture and Chinese herbal medicines have provided me relief and even gotten me through some really rough periods learning how to navigate the depression that accompanies PMR .
For me it's convenient, my wife is an Acupuncturist, and often does no more than putting five or sticks needles in parts of my ear while I listen to an Audible in the recliner. But she also connected me with a mentor of hers who specializes in herbal medicines. The tonic mixed for me has helped with the weaning down process and other issues that are part of being a 74 year old male.
The process for finding Chinese Medicine Practioners who can successfully help requires more than a Google search. Anyone who wants more details are welcome to message me.
I'm not going to pursue this topic more. As uncharted as the science of PMR is, my Practitioners both agree that they would not recommend eliminating Prednisone. And so this topic as effective as it may be for some, could be a counterproductive to a larger conversation.
For me with this, ... the relief and ability to have more function is not complete, but enough to make a difference.
This forum and you folks are awesome, so I wanted to share this unique experience. Apologies to anyone that thought it weird to bring it up.