Need Advice - What drug to Follow Up Evenity

Posted by prehorselover @prehorselover, May 8 5:03pm

I finished my 12th injection of Evenity on March 28th. It’s the only medication I’ve taken. Doctor recommended Prolia. I told her I would do ONE only. Then Reclast, then off drugs. My goal is to be able to ride horses for the rest of my life. I was diagnosed after I broke my shoulder. I’m 66. I suspect I have good bone quality. Started HRT.

Is that a good strategy?

Can you go from Evenity to Forteo?

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

@lbtw

I have avoided the drugs for years even though my DEXA scan scores were not great. In April I had a fall and broke my right hip. I will begin my journey with Evenity this coming week and my doctor also wants me to follow up with reclast to lock in those gains — that I will hopefully have. I have learned so much on this site and appreciate everyone sharing their journey. Good luck

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I just completed my 12th injection of Evenity at the end of March. I had zero substantial side effects. After every injection, I did nothing. I felt a wee bit tired for about four hours. I took the day off and rested to give my body the best chance of recovery.

In addition, I started HRT because hormone loss was the root cause of my disease. I went from osteoporosis to osteopenia in one year. I was nervous about the side effects, but it was a good choice. Wishing you the best of luck!!

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@prehorselover

I just completed my 12th injection of Evenity at the end of March. I had zero substantial side effects. After every injection, I did nothing. I felt a wee bit tired for about four hours. I took the day off and rested to give my body the best chance of recovery.

In addition, I started HRT because hormone loss was the root cause of my disease. I went from osteoporosis to osteopenia in one year. I was nervous about the side effects, but it was a good choice. Wishing you the best of luck!!

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I hope to pick your brain a bit. I am about to complete my 2-year protocol with Tymlos and have some options to hold my gains. Reclast, Prolia, and thru my cardiologist, bioidentical hormones for my very low numbers, which he believes will also help my bones. And yes, my lack of hormones after a full hysterectomy at 38 years old caused my severe bone loss. I am 72 years old so I want to be somewhat confident I’m making good choices for my body. I’m not sure if Evenity is an option after Tymlos…but I have options. Thanks for any info.

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@dooshie

I hope to pick your brain a bit. I am about to complete my 2-year protocol with Tymlos and have some options to hold my gains. Reclast, Prolia, and thru my cardiologist, bioidentical hormones for my very low numbers, which he believes will also help my bones. And yes, my lack of hormones after a full hysterectomy at 38 years old caused my severe bone loss. I am 72 years old so I want to be somewhat confident I’m making good choices for my body. I’m not sure if Evenity is an option after Tymlos…but I have options. Thanks for any info.

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Sorry, forgot to ask…is Evenity a monthly injection?

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@dooshie

I hope to pick your brain a bit. I am about to complete my 2-year protocol with Tymlos and have some options to hold my gains. Reclast, Prolia, and thru my cardiologist, bioidentical hormones for my very low numbers, which he believes will also help my bones. And yes, my lack of hormones after a full hysterectomy at 38 years old caused my severe bone loss. I am 72 years old so I want to be somewhat confident I’m making good choices for my body. I’m not sure if Evenity is an option after Tymlos…but I have options. Thanks for any info.

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Evenity is a monthly injection that can be taken AFTER Tymlos or Forteo, but not the other way around. You can’t go from Evenity to Tymlos/Forteo. It’s intended to be a series of 12 injections. It’s in a similar class as Tymlos and Forteo. Happy to answer any questions you have about Evenity. Best of luck!

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@ceciliamarypatriciafrancis

I'm posting for the first time in a couple of years about this question of follow-up treatment after Evenity. I think I was one of the first people on this site to have completed the 12 month course of Evenity injections. My treatment was considered very successful with scores decreasing from -3.6 and -3.2 to -2.8 and -2.6. I'm 85 years old and had been treated for osteoporosis since my first bone density test when I was 63....mostly with Actonel and then when there was no improvement, with one Prolia injection. Within days of the Prolia injection my sense of taste was weird. I could taste things, but there was some sort of overlay that affected it (coffee in particular tasted terrible), and it took 4 years to return to normal. I no longer was willing to continue with Prolia after that first injection. At this point, my regular provider said that since meds weren't helping after 18 years, it was up to me to decide to continue with Actonel or not. I discontinued it and then a couple of years later, I was counseled to try Evenity, a new treatment on the market. My ENT was pleased with the results, significant improvement: -2.8 and -2.6. She recommended that I follow up with a yearly infusion of Reclast. I didn't want to do that since the 6-month Prolia injection affected me adversely and to me, infusion sounds like chemo, so I went back on Actonel instead. Now, two years later, my latest DEXA shows a decrease and she wants me to do the Reclast.
Some other facts: I had undiagnosed asymptomatic celiac disease only discovered during my first colonoscopy at age 63. This was most likely the cause of my osteoporosis. I haven't had any fractures in years, despite being klutzy.

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ceciliamarypatriciafrancis You could do another round of Evenity and try to grow some more bone before trying something like Reclast to hold on to the bone you have.

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Is that possible? I thought it became less effective towards the end and that’s why 12 injections were recommended.

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@ceciliamarypatriciafrancis

I'm posting for the first time in a couple of years about this question of follow-up treatment after Evenity. I think I was one of the first people on this site to have completed the 12 month course of Evenity injections. My treatment was considered very successful with scores decreasing from -3.6 and -3.2 to -2.8 and -2.6. I'm 85 years old and had been treated for osteoporosis since my first bone density test when I was 63....mostly with Actonel and then when there was no improvement, with one Prolia injection. Within days of the Prolia injection my sense of taste was weird. I could taste things, but there was some sort of overlay that affected it (coffee in particular tasted terrible), and it took 4 years to return to normal. I no longer was willing to continue with Prolia after that first injection. At this point, my regular provider said that since meds weren't helping after 18 years, it was up to me to decide to continue with Actonel or not. I discontinued it and then a couple of years later, I was counseled to try Evenity, a new treatment on the market. My ENT was pleased with the results, significant improvement: -2.8 and -2.6. She recommended that I follow up with a yearly infusion of Reclast. I didn't want to do that since the 6-month Prolia injection affected me adversely and to me, infusion sounds like chemo, so I went back on Actonel instead. Now, two years later, my latest DEXA shows a decrease and she wants me to do the Reclast.
Some other facts: I had undiagnosed asymptomatic celiac disease only discovered during my first colonoscopy at age 63. This was most likely the cause of my osteoporosis. I haven't had any fractures in years, despite being klutzy.

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I am almost done with Evenity 2 more months to go than I will follow up with Reclast . My spine T score when I took the DEXA was -4.6 .

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@kristie2

I am almost done with Evenity 2 more months to go than I will follow up with Reclast . My spine T score when I took the DEXA was -4.6 .

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That's a really negative score. I hope Evenity improves things greatly. Good luck!

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@awfultruth

ceciliamarypatriciafrancis You could do another round of Evenity and try to grow some more bone before trying something like Reclast to hold on to the bone you have.

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Maybe I should check that out with the ENT. I would only do it if it was for a few months, not the whole year. A strange possible side effect: When I was doing the 12 month course of injections, after month 8, I had mysterious rashes on my legs. I brought that up at my 9 month visit, but it was discounted as "not at all likely". When I visited this site after my year was over with positive results, another person remarked on "a rash that felt like bug bites when walking through grass". This was just like I felt. My rash did go away in weeks, but whenever I took my nightly hot bath, I could see tiny red dots under the skin where the rash had been. This February, I had Covid and one of the side effects was the return of the rash. Is this my imagination or could it be a side effect of Evenity? 3 months later, I'm still itchy.

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@prehorselover

Evenity is a monthly injection that can be taken AFTER Tymlos or Forteo, but not the other way around. You can’t go from Evenity to Tymlos/Forteo. It’s intended to be a series of 12 injections. It’s in a similar class as Tymlos and Forteo. Happy to answer any questions you have about Evenity. Best of luck!

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Do you know why you can't do Tymlos/Forteo after Evenity? What if you do something for a year or so in between?

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