← Return to PMR - Decreased prednisone and pain returned

Discussion
Comment receiving replies
@dadcue

Thank-you for this excerpt. Does the following link take you to the entire context?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263906/
I have skimmed this article. Where does it say, "The use of the steroids and the taper actually re-creates the PMR."

I was booted off another PMR forum for saying something similar to this. It reflects my opinion only which I clearly stated. Their position was that cortisol and/or *adrenal insufficiency" had nothing to do with relapses.

The following article spells it out in the Discussion Section:
https://web.archive.org/web/20220128061912id_/https://watermark.silverchair.com/roab091.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAtIwggLOBgkqhkiG9w0BBwagggK_MIICuwIBADCCArQGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMKkw5HAVodIuOOGszAgEQgIIChRZdwI9xNVaeKkeZe7jJU29e41JdjlJegZPHLeIcXuFfxDL4_ClQCcYvNt6V_l53jpdEqiJ1nHLtropSDqcAWJyxfcQoOji4r9vXk8sISkXdcIYyIT5GMieXv-za3al1Avo11SVNV_kd2gtbitSYNr7hCjGUJ7vQ0FaT_Wquuy6p5qeZmxQ2SsxnEu8FBvG4ggQn3rRed8sF56brf4JS3WZj6v5CfalNZJfI2zvqCOB8260V5LCCxIPUQXni5fU3hGLc9N3GPJfA-dK3lB9WuD6fY4JRaRy3mrF9UE7s_LmWAMWbsKguxog9ZYrx0SghOpuPFqEuED0dV-8VNN7m4CKZ87O1BH3WJTxYbX90gVI6H0B9dU8EQMGgVV8_9cV4_Q0LcWvdT7t7u2L6wcOMYqSrM8t3ShzxVsWbxgDG3T7yl5LJYrHDpvVvSqFOy40LlsyShYkqDgH7K4baJEa8XG2ufa1OkWAvF2hC6ksIQ4ttKh9LsfRgKhvG_kqkoiTUlvFGHl8KPN_8I3QNSfY-qFKatySkmY1jqAGsnhyeUgG-kW_U3UT0taF5oHPjwJ2l842ucIhtcqyzzIJtojR-sBqZoyAuXLUfADKB8ULUu_e8xRHJkVHLtR4QN0DNo1DtYWLKjMAjhqOWYceY7_Vivb635cagTqFG9_lkJM6MIxuHr7-SlobUtBsDt1OblfHN0vxL3yTP027pNGxB2Lb5MgS1xzvGAh8T1lH_9D3vczZSUwIhnV_FMZ7ps2iRPvq-en2Y7V7t2cGL9LussoNdi0rKuFIZNfqPrLhhwsbuiuoobANURuZxe7st3I8q4xIvTlyDN85V6X3AX6dtPEhYOO-2PNwXrg#:~:text=Relapses%20are%20common%20in%20patients,ficult%20to%20distinguish%20%5B20%5D.

Jump to this post


Replies to "Thank-you for this excerpt. Does the following link take you to the entire context? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263906/ I..."

I have to find it. I copied it from an NIH document and posted it on a facebook PMR site. I made a copy of it in my email. So it was word for word but I need to find the document search. Same happened to me on the facebook page. I am not an expert but my wife has glioblastoma. Drug of choice is dexamethasone. I have researched steroids for 3 years. Mainly because I further poison her body and reduce her immune system every day when I give her the medication. Her oncologists all agree with us but just say "she has terminal cancer, make her comfortable" I have tried numerous times to get her off and it immediately increases the inflammation. Not good in the brain. I got PMR probably from the stress. I used Dex to reduce it. Took 6 months but I finally had clear markers and just stopped. Kicked my butt for about 2 weeks but I got off. I kicked it. PMR is real because it shows up when your not on a steroid. But the steroid mimics the pain into a vicious cycle that everyone sees as a flare. Your right in my opinion. Most everyone is just hooked on the steroid.

I also saw and NIH study of 25 patients they attempted to take off long term steroid use. None of the 25 were able to wean completely. I would have to find that one also. So the cortisol production is a very real issue. No one is crazy thinking they are weak and just cant do it. It also increases the pain which then increases the inflammation and restarts the whole process. So cortisol deficiency is real and PMR is real. I see everyone get to 5-7 mg and say they have a flare and had to go back. Its a never ending story.

your comment of where that statement is located is in the link you sent. You go down several pages until you see a chart Acute and Chronic. The comment is in the footnotes of the chart.