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11 anniversaries since diagnosis of stage 4 prostate cancer

Prostate Cancer | Last Active: 4 hours ago | Replies (83)
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@wellness100

You brought up an interesting point about PSA. What is the lowest level of PSA detected by PSMA Pet scan which indicates cancer is still present, or recurrence? The current consensus is above 0.1 or 0.2. Some suggest it might be 0.5. Are there any recent studies or clinical experiences which indicate otherwise? Just inviting discussion.
Dont mind me. I am just another layman trying to make some sense of the whole thing.

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Replies to "You brought up an interesting point about PSA. What is the lowest level of PSA detected..."
northoftheborder | @northoftheborder | May 25 1:12pm

Here's a study (pretty old now) challenging the then-accepted 0.2 PSA as the threshold for recurrence, and identifying < 0.03 uPSA (ultrasensitive PSA) as the most-reliable predictor. It focused only on patients who'd had radical prostatectomies, so it's not necessarily fully-applicable to people who had only radiation and/or ADT and/or ARSI:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527538/

That doesn't mean that if your PSA rises back to 0.1 after treatment bad things are happening; just that best practice would be to start monitoring you more closely sooner, BEFORE the PSA climbs to 0.2.

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