Alyse, I have moderate rheumatoid arthritis (RA) and have been on those toxic medications (Methotraxate, Celeblex and Orencia, but switched to Simponi ~ 9 months ago due to the inconvenience of traveling overseas with the med that requires refrigeration) for the past twelve years. I am on a crusade to find ways to reduce those toxic medications. Since I started the plant based diet and gluten free (inspire by the book "Eat to Live" by Joel Furhman), I was able to reduce my weekly methotrexate by 1/3. I have not taken any Celeblex in the past two months (I used to take It at least twice a week). When I mentioned this to my RA Doctor as I started this diet, she was skeptical but encourage me to try and see how it go. My Joints pain and fatigue have improved quite a bit. I have not felt this way in a long time, so it is very encouraging. Everyone chronically illness is different, so I am not advocating other to follow the same diet. All I am trying here to share my experience and encourage others to try different ways to find solutions that help alleviate the symptoms.