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Hi and thanks for the reply. My PSA is a 4.3, but I'm in Canada and I think they measure it differently. However, I was told it is within the normal range. I think it was just standard PSA as the ISO does not ring a bell. My biopsy was not MRI guided (just ultrasound), was 12 cores and only 1 core had the cancer and they told me it was a small amount. However, the biopsy also said my prostate was only 37cc in size, and the followup MRI said it was 62 cc, and the doctor told me the MRI is far more accurate, so that makes me wonder if they missed something in the biopsy as you say. The MRI didn't detect any tumors. Can I ask what treatment you had and how effective it was? Thanks Joe
Replies to "Hi and thanks for the reply. My PSA is a 4.3, but I'm in Canada and..."
When I was first diagnosed with Gleason 6 low risk cancer in 2020 I opted for focal brachytherapy. Unfortunately, I was under diagnosed and the cancer came back with a vengeance in 2023. I’m now on a journey with Stage 3 locally metastatic prostate cancer. That’s why I’m on this forum; to help inform other men so they have the best chance to get the best diagnosis and treatment possible the first time around.
Hope this helps you!
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Hi Joe. Sorry for the late reply. Unusually busy day.
As far as I can tell, PSA readings in Canada and the United States are interchangeable. You can find more information here: https://www.inspire.com/groups/zero-prostate-cancer/discussion/comparing-canadian-psa-levels-to-american-psa-levels/?p=1&sort_order=DESC&reply_structure=unthreaded
A ISO-PSA test is an advanced test that helps determine if a higher PSA number is related to prostate cancer. It is available in Canada. More info here: https://pcstoronto.ca/2017/07/02/new-isopsa-assay-detects-prostate-cancer-precisely-current-tests/
The fact that your MRI didn’t notice anything is interesting. Do you know if it was a 3 Tesla MRI with and without contrast. If the MRI was done on older equipment (1.5 T) it might not have had the resolution to spot significant cancer.
More info here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373864/