Keytruda was a life saver for my husband with pancreatic cancer which metastasized to the adrenal glands 8 months after chemo and excision. We were thrilled that he fit the guidelines for it. Clearly the side effects were minimal as he went through it. He felt he had his life back with the treatment within 2 months the metastasis had disappeared and stayed out of site at least. He would still use it again. He was on it for 2 years which we understand is usually as long as a person is on it for. He had some itchiness during that time that was controlled with medication. At the end of the 2 years ,He had not stopped it when he began having a very rare side effect for Keytruda, an autoimmune illness. They stopped the Keytruda. The side effect was mucositis in the mouth. This has been abated with steroids and is going into remission with another medication. Although this was difficult, once the biopsy was made and diagnosis & treatment was in place he has responded well. The blessing has been he is finishing his 5th year since his PC diagnosis.

The bearable side effects during treatment were exhaustion, some nausea, bouts of itching, and feeling cold all the time. I stayed grateful each day, still do.
There are no signs of cancer. CatScans are done every three months and frequently will less as time goes on.
I was on Keytruda for two years, ended treatment in November. Unfortunately, a few months later, the Keytruda caused pancreatitis.
and this week I was told it is chronic pancreatitis. The issues continue and we are now experimenting with a variety of medications with the hope we can minimize these side effects. My doctor disclosed she is treating two other patients with the same issues, and they are responding well to their prescribed meds.
I wish you and your husband the very best on this journey. To be cancer free is a blessing. Live this journey one day at a time. Keytruda has been a life saving drug for me. And I am so grateful this treatment is available for others.