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← Return to Prednisone for over a year along with Kevzara for last 5 months
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Prednisone for over a year along with Kevzara for last 5 months
Polymyalgia Rheumatica (PMR) | Last Active: Jun 3 11:35am | Replies (47)Comment receiving replies
Actually Kevzara has few side effects and the ones which exist only affect a few people. They have to list anything anybody has had as far as side effects. Far less than methotrexate or prednisone. I know some people have a reaction at the injection site. I’ve been on it since December. It has been a game changer for me. My doc watches my liver function which was slightly elevated for two months, and I’ve been warned about watching out for infections but other than that..no problems and I am finally back down to 7mg of pred. My rheumatologists had about 10 patients with pmr and on Kevzara and none have had any problems.
Replies to "Actually Kevzara has few side effects and the ones which exist only affect a few people...."
I'm not able to create a link but this is the URL for the report on the phase 3 clinical trial for Zevzara used for PMR. It was only 118 patients. If I read it correctly, 28% of the group taking Kevzara were off prednisone in a year versus 10% for the placebo. It discusses lab abnormalities and side effects, which appear to be low. I will start Kevzara this week. Copy/paste should get you to the paper.
https://www.nejm.org/doi/full/10.1056/NEJMoa2303452
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Thats good to know on the drug. Maybe in the future Kevzara can be prescribed to treat PMR without having to use steroids. I can also see where Kevzara might be helpful in your taper off steroids by keeping the PMR inflammation at bay. My concern is for those that are taking both and unable to taper steroid below the pain level of withdrawal. Your about to enter that zone. I wish you luck. Thanks for the advice on the Kevzara.