I have had diabetic foot neuropathy for several years and have found that Nike Air Monarchs provided the best support and pain relief. I recently got some diabetic shoes from a local store. They gave me a size 10 1/2 shoe based on their measurement. They are comfortable after only a short period of time but feel quite restrictive. I am currently wearing a Nike Air Monarch, a size 12 and extra wide (4E). The extra size acommodates my feet quite well and does not encourage callouses. I have had a callous on my right heel split on occasion and be a real problem to heel. I have a spot that has never healed and is always painful and delicate. It's too early for me to issue an opinion on the diabetic shoe so the best I can recommend is the Nike.